nope, i run that axle, the f250 axle uses a bigger knuckle, also has a 5 stud spindle where the waggy has a 6 stud.
edit: hell i may be wrong, ive been searching on pirate for a while. i just remember having a 6 bolt flattop knuckle (suposivly from a waggy) and sticking it up to my inner C's and it was way to small, also very small compared to my 5 stud knuckle. also my spindle has the exact same bolt pattern as a ford D60, just needs to be alittle bigger for to fit the 30 spline outters and a hell a lot bigger for 35 splined shafts
